E-AB-12853
PTPRM Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-12853
- Additional Names:
- PTPRL1,PTPRM,Protein tyrosine phosphatase mu,Protein tyrosine phosphatase receptor type M,Protein tyrosine phosphatase receptor type mu polypeptide,Protein-tyrosine phosphatase mu,Ptprm,R PTP mu,R-PTP-mu,Receptor type tyrosine protein phosphatase ,hR PTPu
- Application:
- IHC
- Concentration:
- 0.4 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human PTPRM
- Uniprot:
- P28827
- Synonyms:
- hR-PTPu;protein tyrosine phosphatase mu;protein tyrosine phosphatase, receptor type, mu polypeptide;PTPRL1;R-PTP-MU;receptor-type tyrosine-protein phosphatase mu;RPTPM;RPTPU
- Extra Details:
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, whicHuman, Mouseay be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.
- Shipping Conditions:
- Blue Ice