E-AB-12851
PTN Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-12851
- Additional Names:
- HARP,HB-GAM,HBBM,HBGAM,HBGF-8,HBGF8,HBNF,HBNF-1,HBNF1,Heparin binding growth associated molecule,Heparin binding growth factor 8,Heparin binding neurite outgrowth promoting factor 1,Heparin-bi,Heparin-binding brain mitogen,heparin affin regulatory protein
- Application:
- WB
- Concentration:
- 0.3 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human PTN
- Uniprot:
- P21246
- Synonyms:
- HARP;HB-GAM;HBBM;HBGF-8;HBGF8;HBNF;HBNF-1;heparin affin regulatory protein;heparin-binding brain mitogen;heparin-binding growth factor 8;heparin-binding growth-associated molecule;heparin-binding neurite outgrowth promoting factor;heparin-binding neurite outgrowth-promoting factor 1;NEGF1;OSF-1;osteoblast-specific factor 1;pleiotrophin;pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1)
- Extra Details:
- Pleiotrophin (PTN) also known as heparin-binding brain mitogen (HBBM) or heparin-binding growth factor 8 (HBGF-8) or neurite growth-promoting factor 1 (NEGF1) or heparin affinity regulatory peptide (HARP) or heparin binding growth associated molecule (HB-GAM) is a protein that in humans is encoded by the PTNgene.Pleiotrophin is an 18-kDa growth factor that has a high affinity for heparin.It is structurally related to midkine and retinoic acid induced heparin-binding protein.Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells.Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation.
- Shipping Conditions:
- Blue Ice