E-AB-12839
PDGFA Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-12839
- Additional Names:
- PDGF A,PDGF A chain,PDGF subunit A,PDGF-1,PDGF1,PDGFA,Pla,Platelet derived growth factor alpha chain,Platelet derived growth factor alpha isoform 2 preproprotein,Platelet derived growth factor alpha polypeptide,Platelet-derived growth factor A chain
- Application:
- IHC
- Concentration:
- 1.1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human PDGFA
- Uniprot:
- P04085
- Synonyms:
- PDGF A-chain;PDGF subunit A;PDGF-1;PDGF-A;PDGF1;Platelet-derived growth factor A chain;platelet-derived growth factor A-chain;platelet-derived growth factor alpha chain;platelet-derived growth factor alpha polypeptide;platelet-derived growth factor subunit A
- Extra Details:
- The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis, knockout mice die either as embryos or shortly after birth. Two splice variants have been identified for this gene.
- Shipping Conditions:
- Blue Ice