E-AB-12793
MYSM1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-12793
- Additional Names:
- 2A-DUB,2ADUB,Histone H2A deubiquitinase,Histone H2A deubiquitinase MYSM1,KIAA1915,MYS,MYSM 1,Myb like,Myb like SWIRM and MPN domains 1,Myb-like,SWIRM and MPN domain containing protein,SWIRM and MPN domains 1,mysm1
- Application:
- IHC
- Concentration:
- 0.5 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human MYSM1
- Uniprot:
- Q5VVJ2
- Synonyms:
- 2A-DUB;2ADUB;BMFS4;deubiquitinase MYSM1;histone H2A deubiquitinase MYSM1;myb-like, SWIRM and MPN domain-containing protein 1
- Extra Details:
- Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.Component of a large chromatin remodeling complex, at least composed of MYSM1, PCAF, RBM10 and KIF11/TRIP5. Binds histones
- Shipping Conditions:
- Blue Ice