E-AB-12706
AGXT Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-12706
- Additional Names:
- AGT,AGT1,AGXT1,Agxt,Alanine glyoxylate aminotransferase,Alanine glyoxylate aminotransferase3,Alanine--glyoxylate aminotransferase,EC 2.6.1.44,EC 2.6.1.51,Hepatic peroxisomal alanine glyoxylate aminotransferase,Hepatic peroxisomal alanine:glyoxylate aminot
- Application:
- WB
- Concentration:
- 0.6 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human AGXT
- Uniprot:
- P21549
- Synonyms:
- AGT;AGT1;AGXT1;Alanine--glyoxylate aminotransferase;alanine-glyoxylate aminotransferase;hepatic peroxisomal alanine:glyoxylate aminotransferase;L-alanine: glyoxylate aminotransferase 1;PH1;serine--pyruvate aminotransferase;SPAT;SPT;TLH6
- Extra Details:
- Serine-pyruvate aminotransferase is an enzyme that in humans is encoded by the AGXT gene. This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. Defects in AGXT are the cause of hyperoxaluria primary type 1 (HP1), also known as primary hyperoxaluria type I (PH1) and oxalosis I. HP1 is a rare autosomal recessive inborn error of glyoxylate metabolism characterized by increased excretion of oxalate and glycolate, and the progressive accumulation of insoluble calcium oxalate in the kidney and urinary tract.
- Shipping Conditions:
- Blue Ice