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E-AB-12686

ABCD4 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-12686
Additional Names:
69 kDa peroxisomal ABC transporter,ABC 41,ABC41,ABCD 4,ABCD4,ATP binding cassette sub family D (ALD) member 4,ATP binding cassette sub family D member 4,ATP-binding cassette sub-family D member 4,EST352188,MAHCJ,MGC105956,P70R,P79R,Peroxisomal membr
Application:
WB
Concentration:
0.3 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human ABCD4
Uniprot:
O14678
Synonyms:
69 kDa peroxisomal ABC-transporter;ABC41;ATP-binding cassette sub-family D member 4;ATP-binding cassette, sub-family D (ALD), member 4;EST352188;lysosomal cobalamin transporter ABCD4;MAHCJ;P70R;P79R;Peroxisomal membrane protein 1-like;peroxisomal membrane protein 69;PMP69;PMP70-related protein;PXMP1-L;PXMP1L
Extra Details:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis.
Shipping Conditions:
Blue Ice