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E-AB-12661

HNF1B Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-12661
Additional Names:
FJHN,HNF 1B,HNF 2,HNF-1-beta,HNF-1B,HNF1 beta,HNF1 homeobox B,HNF1B,HNF1beta,HNF2,HPC11,Hepatocyte nuclear factor 1 beta,Hepatocyte nuclear factor 1-beta,Homeoprotein LF B3,Homeoprotein LFB3,LF B3,LFB3,MODY 5,MODY5,TCF,TCF 2,TCF 2 protein,TCF-2,TCF2
Application:
IHC
Concentration:
0.9 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human HNF1B
Uniprot:
P35680
Synonyms:
ADTKD3;FJHN;hepatocyte nuclear factor 1-beta;HNF-1-beta;HNF-1B;HNF1 beta A;HNF1beta;HNF2;homeoprotein LFB3;HPC11;LF-B3;LFB3;MODY5;RCAD;T2D;TCF-2;TCF2;Transcription factor 2;transcription factor 2, hepatic;Variant hepatic nuclear factor 1;VHNF1
Extra Details:
This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Shipping Conditions:
Blue Ice