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E-AB-12640

SLC12A6 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-12640
Additional Names:
ACCPN,Electroneutral potassium-chloride cotransporter 3,Furosemide sensitive KCl cotransporter 3,Gaxp,K-Cl cotransporter 3,KCC 3,KCC 3A,KCC 3B,KCC3,KCC3 A,KCC3 B,KCC3A,KCC3B,Potassium chloride cotransporter 3,Potassium chloride cotransporter KCC3a S3,S12A
Application:
IHC
Concentration:
0.4 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human SLC12A6
Uniprot:
Q9UHW9
Synonyms:
ACCPN;electroneutral potassium-chloride cotransporter 3;K-Cl cotransporter 3;KCC3;KCC3A;KCC3B;potassium chloride cotransporter 3;potassium chloride cotransporter KCC3a-S3;potassium-chloride transporter-3a;potassium-chloride transporter-3b;solute carrier family 12 (potassium/chloride transporter), member 6;solute carrier family 12 (potassium/chloride transporters), member 6;solute carrier family 12 member 6
Extra Details:
This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy.
Shipping Conditions:
Blue Ice