E-AB-12624
PFN2 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-12624
- Additional Names:
- D3S1319E,PFL,PFN 2,PROF2,Pfn2,Profilin II,Profilin-2,Profilin2,ProfilinII
- Application:
- IHC, WB
- Concentration:
- 0.3 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human PFN2
- Uniprot:
- P35080
- Synonyms:
- D3S1319E;PFL;profilin II;profilin-2
- Extra Details:
- The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
- Shipping Conditions:
- Blue Ice