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E-AB-12506

HMGB2 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-12506
Additional Names:
C80539,HMG 2,HMG B2,HMG-2,HMG2,HMGB2,High mobility group (nonhistone chromosomal) protein 2,High mobility group box 2,High mobility group protein 2,High mobility group protein B2
Application:
WB
Concentration:
0.9 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human HMGB2
Uniprot:
P26583
Synonyms:
high mobility group protein 2;high mobility group protein B2;high-mobility group (nonhistone chromosomal) protein 2;HMG-2;HMG2
Extra Details:
This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
Shipping Conditions:
Blue Ice