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E-AB-12397

ERK1/2 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-12397
Additional Names:
ERK1,ERK1/2,ERK2
Application:
IHC, WB
Concentration:
0.5 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human MAPK1/MAPK3
Uniprot:
P27361, P28482
Synonyms:
ERK;ERK-1;ERK-2;ERK1;ERK2;ERT1;ERT2;extracellular signal-regulated kinase 1;extracellular signal-regulated kinase 2;extracellular signal-related kinase 1;HS44KDAP;HUMKER1A;insulin-stimulated MAP2 kinase;MAP kinase 1;MAP kinase 2;MAP kinase isoform p42;MAP kinase isoform p44;MAPK 1;MAPK 2;MAPK2;microtubule-associated protein 2 kinase;mitogen-activated protein kinase 1;mitogen-activated protein kinase 2;mitogen-activated protein kinase 3;NS13;p38;p40;p41;p41mapk;p42-MAPK;P42MAPK;p44-ERK1;p44-MAPK;P44ERK1;P44MAPK;PRKM1;PRKM2;PRKM3;protein tyrosine kinase ERK2
Extra Details:
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Shipping Conditions:
Blue Ice