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E-AB-12355

Cyclin D3 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-12355
Additional Names:
CCND 3,CCND3,Ccnd3,CyclinD3,D3 type cyclin,G1 S specific cyclin D3,G1/S specific cyclin D3,G1/S-specific cyclin-D3
Application:
IHC
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human CCND3
Uniprot:
P30281
Synonyms:
D3-type cyclin;G1/S-specific cyclin-D3
Extra Details:
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb.
Shipping Conditions:
Blue Ice