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E-AB-12280

ASCL1 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-12280
Additional Names:
Achaete scute complex homolog 1,Achaete scute complex homolog like 1,Achaete scute complex homologue 1,Achaete scute complex homologue like 1,Achaete scute complex like 1,Achaete scute family bHLH transcription factor 1,Achaete scute protein,Achaete-scute
Application:
IHC
Concentration:
0.2 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human ASCL1
Uniprot:
P50553
Synonyms:
achaete scute protein;achaete-scute complex homolog 1;achaete-scute complex-like 1;achaete-scute homolog 1;ASH-1;ASH1;bHLHa46;class A basic helix-loop-helix protein 46;HASH1;MASH1
Extra Details:
This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.
Shipping Conditions:
Blue Ice