E-AB-12255
LOX Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-12255
- Additional Names:
- LYOX,Lysyl oxidase,MGC105112,Protein lysine 6 oxidase,Protein-lysine 6-oxidase,lox
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human LOX
- Uniprot:
- P28300
- Synonyms:
- AAT10;Lysyl oxidase;protein-lysine 6-oxidase
- Extra Details:
- The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice