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E-AB-12248

RHOB Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-12248
Additional Names:
ARH6,ARHB,Aplysia RAS-related homolog 6,H6,MST081,MSTP081,RHOB,RHOH6,Rho cDNA clone 6,Rho related GTP binding protein RhoB Precursor,Rho-related GTP-binding protein RhoB,Rhob,member B,oncogene RHO H6,ras homolog family member B,ras homolog gene family
Application:
WB
Concentration:
0.4 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human RHOB
Uniprot:
P62745
Synonyms:
Aplysia RAS-related homolog 6;ARH6;ARHB;h6;MST081;MSTP081;oncogene RHO H6;ras homolog gene family, member B;rho cDNA clone 6;rho-related GTP-binding protein RhoB;RHOH6
Extra Details:
Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene.RHOB is a member of the Rho GTP-binding protein family.Mediates apoptosis in neoplastically transformed cells after DNA damage. It is not necessary for development but affects cell adhesion and growth factor signaling in transformed cells. It plays a negative role in tumorigenesis as deletion causes tumor formation. It involved in intracellular protein trafficking of a number of proteins, and serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.
Shipping Conditions:
Blue Ice