E-AB-11440
NEDD4L Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-11440
- Additional Names:
- E3 ubiquitin protein ligase NEDD4 like protein,E3 ubiquitin-protein ligase NEDD4-like,KIAA0439,NED4L,NEDD4 2,NEDD4 2c,NEDD4-2a,NEDD4.2,NEDD4L,NEDD4La,NEDD4Lb,NEDD4Lc,NEDD4Ld,NEDD4Le,NEDD4Lf,NEDD4Lg,NEDD4Lh,NEDD4b,NEDL3,Nedd4-2,Neural precursor cell expres
- Application:
- IHC
- Concentration:
- 0.4 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human NEDD4L
- Uniprot:
- Q96PU5
- Synonyms:
- E3 ubiquitin-protein ligase NEDD4-like;HECT-type E3 ubiquitin transferase NED4L;hNEDD4-2;NEDD4-2;NEDD4.2;neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase;PVNH7;RSP5;ubiquitin-protein ligase Rsp5
- Extra Details:
- This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases.HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation.The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC.Single nucleotide polymorphisms in this gene may be associated with essential hypertension.
- Shipping Conditions:
- Blue Ice