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E-AB-11421

DAN Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-11421
Additional Names:
D1S1733E,DAN,DAN domain family member 1,DAND 1,DAND1,Differential screening selected gene aberrant in neuroblastoma,MGC8972,NB,NBL 1,Neuroblastoma,Neuroblastoma candidate region suppression of tumorigenicity 1,Neuroblastoma suppression of tumorigenicity 1
Application:
IHC
Concentration:
0.3 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human NBL1
Uniprot:
P41271
Synonyms:
C1orf151-NBL1;C1orf151-NBL1 read-through protein;D1S1733E;DAN;DAN domain family member 1;DAND1;differential screening-selected gene aberrant in neuroblastoma;MICOS10-NBL1 read-through protein;MINOS1-NBL1;MINOS1-NBL1 readthrough;NB;NBL1;neuroblastoma 1, DAN family BMP antagonist;neuroblastoma candidate region, suppression of tumorigenicity 1;neuroblastoma suppressor of tumorigenicity 1;NO3;Protein N03;Zinc finger protein DAN
Extra Details:
This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules.These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors.They may thus play an important role during growth and development.
Shipping Conditions:
Blue Ice