E-AB-11418
PPP1R12A Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-11418
- Additional Names:
- M130,MBS,MYPT1,Myosin binding subunit,Myosin phosphatase target subunit 1,Myosin phosphatase targeting subunit 1,Myosin phosphatase-targeting subunit 1,PPP1R12A,Protein phosphatase 1 regulatory ,Protein phosphatase 1 regulatory inhibitor subunit 12A
- Application:
- WB
- Concentration:
- 0.4 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human PPP1R12A
- Uniprot:
- O14974
- Synonyms:
- GUBS;M130;MBS;myosin binding subunit;myosin phosphatase-targeting subunit 1;myosin phosphatase, target subunit 1;MYPT1;protein phosphatase 1 regulatory subunit 12A;protein phosphatase 1, regulatory (inhibitor) subunit 12A;protein phosphatase myosin-binding subunit
- Extra Details:
- Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC.
- Shipping Conditions:
- Blue Ice