E-AB-11380
TAB3 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-11380
- Additional Names:
- MAP3K7IP 3,Mitogen-activated protein kinase kinase kinase 7-interacting protein 3,NAP1,NF-kappa-B-activating protein 1,NFkB activating protein 1,TAB-3,TAB3,TAK1 binding protein 3,TAK1-binding protein 3,TGF-beta-activated kinase 1 and MAP3K7-binding p,Tab3
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human TAB3
- Uniprot:
- Q8N5C8
- Synonyms:
- MAP3K7IP3;mitogen-activated protein kinase kinase kinase 7 interacting protein 3;Mitogen-activated protein kinase kinase kinase 7-interacting protein 3;NAP1;NF-kappa-B-activating protein 1;NFkB activating protein 1;TAB-3;TAK1-binding protein 3;TGF-beta activated kinase 1 and MAP3K7 binding protein 3;TGF-beta-activated kinase 1 and MAP3K7-binding protein 3;TGF-beta-activated kinase 1-binding protein 3
- Extra Details:
- The product of this gene functions in the NF-kappaB signal transduction pathway.The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1.Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor.The human genome contains a related pseudogene.
- Shipping Conditions:
- Blue Ice