E-AB-11375
LZTFL1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-11375
- Additional Names:
- 5530402H04Rik,6130400H19Rik,AI414725,AW048545,BBS17,DKFZp686H2076,FLJ36386,LZTFL 1,Leucine zipper transcription factor like 1,Leucine zipper transcription factor like protein 1,Leucine zipper transcription factor-like protein 1,Lztfl1,Lztfl1 leucine zippe
- Application:
- IHC, WB
- Concentration:
- 0.4 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human LZTFL1
- Uniprot:
- Q9NQ48
- Synonyms:
- BBS17;leucine zipper transcription factor-like protein 1
- Extra Details:
- This gene encodes a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in this gene cause a form of Bardet-Biedl Syndrome, a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This gene may also function as a tumor suppressor, possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. Alternative splicing of this gene results in multiple transcript variants.
- Shipping Conditions:
- Blue Ice