CD242 Polyclonal Antibody

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£106.20

Was £118.00

SKU:: E-AB-11318
Additional Names:: CD242,CD242 antigen,ICAM-4,ICAM4,Icam4,Intercellular adhesion molecule 4,LW,LW blood group protein,Landsteiner Wiener blood group glycoprotein,Landsteiner-Wiener blood group glycoprotein
Application:: IHC
Concentration:: 0.2 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant protein of human ICAM4
Uniprot:: Q14773
Synonyms:: CD242;CD242 antigen;intercellular adhesion molecule 4;intercellular adhesion molecule 4 (LW blood group);Landsteiner-Wiener blood group antigen a;Landsteiner-Wiener blood group glycoprotein;LW;LW antigen a
Extra Details:: This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100, Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms.