E-AB-11311
HSD3B7 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-11311
- Additional Names:
- 3 beta HSD VII,3 beta hydroxy Delta(5) C27 steroid oxidoreductase,3 beta hydroxysteroid dehydrogenase type 7,3 beta hydroxysteroid dehydrogenase type VII,7 alpha diol 3 beta dehydrogenase,AI195443,BB098564,C(27) 3 beta HSD,Cca2,Cholest 5 ene 3 beta,Conflu
- Application:
- IHC
- Concentration:
- 0.3 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human HSD3B7
- Uniprot:
- Q9H2F3
- Synonyms:
- 3 beta-hydroxy-delta 5-C27-steroid oxidoreductase;3 beta-hydroxysteroid dehydrogenase type 7;3 beta-hydroxysteroid dehydrogenase type VII;3-beta-HSD VII;3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase;c(27) 3-beta-HSD;C(27)-3BETA-HSD;CBAS1;cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase;PFIC4;SDR11E3;short chain dehydrogenase/reductase family 11E, member 3
- Extra Details:
- This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice