E-AB-11270
Glucocorticoid Receptor Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-11270
- Additional Names:
- GCCR,GCR,GCRST,GR,GRL,Glucocorticoid receptor,Grl1,Nuclear receptor subfamily 3 group C member 1,glucocorticoid nuclear receptor variant 1,group C,member 1 (glucocorticoid receptor),nr3c1,nuclear receptor subfamily 3
- Application:
- IHC
- Concentration:
- 0.4 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human NR3C1
- Uniprot:
- P04150
- Synonyms:
- GCCR;GCR;GCRST;glucocorticoid nuclear receptor variant 1;glucocorticoid receptor;GR;GRL;Nuclear receptor subfamily 3 group C member 1;nuclear receptor subfamily 3 group C member 1 variant hGR-B(54);nuclear receptor subfamily 3 group C member 1 variant hGR-B(77);nuclear receptor subfamily 3 group C member 1 variant hGR-B(93);nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
- Extra Details:
- This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance.
- Shipping Conditions:
- Blue Ice