E-AB-11232
FGFR1OP Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-11232
- Additional Names:
- FOP
- Application:
- IHC
- Concentration:
- 0.7 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human FGFR1OP
- Uniprot:
- O95684
- Synonyms:
- centrosomal protein 43;FGFR1 oncogene partner;FGFR1OP;fibroblast growth factor receptor 1 oncogene partner;FOP
- Extra Details:
- This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6,8)(q27,p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified.
- Shipping Conditions:
- Blue Ice