E-AB-11121
CYP27A1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-11121
- Additional Names:
- 12-alpha-triol 26-hydroxylase,12-alpha-triol 27-hydroxylase,5-beta-cholestane-3-alpha,7-alpha
- Application:
- IHC
- Concentration:
- 0.6 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human CYP27A1
- Uniprot:
- Q02318
- Synonyms:
- 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 26-hydroxylase;5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 27-hydroxylase;5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase;cholestanetriol 26-monooxygenase;CP27;CTX;CYP27;cytochrome P-450C27/25;cytochrome P450 27;cytochrome P450, family 27, subfamily A, polypeptide 1;cytochrome P450, subfamily XXVIIA (steroid 27-hydroxylase, cerebrotendinous xanthomatosis), polypeptide 1;sterol 26-hydroxylase, mitochondrial;sterol 27-hydroxylase;vitamin D(3) 25-hydroxylase
- Extra Details:
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease.
- Shipping Conditions:
- Blue Ice