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E-AB-11062

SEPT7 Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:
E-AB-11062
Additional Names:
CDC10,CDC10 protein homolog,CDC3,Cell division cycle 10,NBLA02942,SEPT7,SEPT7A,Septin 7,Septin-7
Application:
IHC, WB
Concentration:
0.5 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human SEPT7
Uniprot:
Q16181
Synonyms:
CDC10;CDC10 (cell division cycle 10, S. cerevisiae, homolog);CDC10 protein homolog;CDC3;NBLA02942;SEPT7;SEPT7A;septin 7 variant 4;septin-7
Extra Details:
This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19
Shipping Conditions:
Blue Ice