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E-AB-11014

BUB1 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-11014
Additional Names:
BUB1,BUB1 budding uninhibited by benzimidazoles 1 homolog,BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast),BUB1 mitotic checkpoint serine/threonine kinase,BUB1A,BUB1L,Bub1,Budding uninhibited by benzimidazoles 1 (,S. cerevisiae,homolog of
Application:
IHC
Concentration:
0.5 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human BUB1
Uniprot:
O43683
Synonyms:
BUB1 budding uninhibited by benzimidazoles 1 homolog;BUB1A;BUB1L;budding uninhibited by benzimidazoles 1 homolog;hBUB1;mitotic checkpoint serine/threonine-protein kinase BUB1;mitotic spindle checkpoint kinase;putative serine/threonine-protein kinase
Extra Details:
This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.
Shipping Conditions:
Blue Ice