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E-AB-10990

ATXN1 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-10990
Additional Names:
ATX1,Ataxin-1,Atxn1,D6S504E,OTTHUMP00000016065,SCA1,Spinocerebellar ataxia type 1 protein,alternative ataxin1
Application:
IHC
Concentration:
0.4 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human ATXN1
Uniprot:
P54253
Synonyms:
alternative ataxin1;ataxin-1;ATX1;D6S504E;SCA1;spinocerebellar ataxia type 1 protein
Extra Details:
The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord.Clinically, ADCA has been divided into three groups: ADCA types I-III.ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes.ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders.Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions.
Shipping Conditions:
Blue Ice