E-AB-10976
AURKAIP1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-10976
- Additional Names:
- 28S ribosomal protein S38,AIP,AKIP,AURKA interacting protein,AURKA-interacting protein,AURKAIP 1,Aurkaip1,Aurora A kinase interacting protein,Aurora kinase A interacting protein 1,Aurora kinase A-interacting protein,FLJ20608,MRP-S38,mitochondrial
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human AURKAIP1
- Uniprot:
- Q9NWT8
- Synonyms:
- 28S ribosomal protein S38, mitochondrial;AIP;AKIP;AURKA-interacting protein;aurora kinase A-interacting protein;aurora-A kinase interacting protein;mitochondrial small ribosomal subunit protein mS38;MRP-S38
- Extra Details:
- AKIP (AURKA-interacting protein), also known as AURKAIP1 (aurora kinase A interacting protein 1) or AIP, is a 199 amino acid protein that localizes to the nucleus and is ubiquitously expressed, with highest levels present in testis, heart and skeletal muscle. Interacting specifically with ARK-1 (aurora kinase 1), AKIP functions to induce the proteasomal-dependent degradation of ARK-1, thereby acting as a negative regulator of ARK-1 activity. AKIP is encoded by a gene which maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
- Shipping Conditions:
- Blue Ice