E-AB-10975
IKZF3 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-10975
- Additional Names:
- AIO,Aiolos,IKAROS family zinc finger 3,IKAROS family zinc finger 3 (Aiolos),IKZF 3,IKZF3,Ikaros family zinc finger protein 3,Zinc finger pr,Zinc finger protein Aiolos,Zinc finger protein subfamily 1A 3 (Aiolos),zinc finger DNA binding protein Aiolos
- Application:
- IHC
- Concentration:
- 0.7 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human IKZF3
- Uniprot:
- Q9UKT9
- Synonyms:
- AIO;AIOLOS;Ikaros family zinc finger protein 3;IMD84;zinc finger DNA binding protein Aiolos;zinc finger protein Aiolos;zinc finger protein, subfamily 1A, 3 (Aiolos);ZNFN1A3
- Extra Details:
- This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.
- Shipping Conditions:
- Blue Ice