E-AB-10974
AIM2 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-10974
- Additional Names:
- AIM 2,AIM2,Absent in melanoma 2,Aim2,Interferon-inducible protein AIM2,OTTHUMP00000035296,PYHIN4
- Application:
- IHC
- Concentration:
- 0.8 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human AIM2
- Uniprot:
- O14862
- Synonyms:
- Absent in melanoma 2;interferon-inducible protein AIM2;PYHIN4
- Extra Details:
- Interferon-inducible protein AIM2 (Absent in melanoma 2) is a 343 amino acid protein belonging to the HIN-200 family.Induced by IFN- , AIM2 is thought to act as a tumor suppressor by repressing NF B transcriptional activity.Localized to the nucleus, AIM2 contains one DAPIN domain and one HIN-200 domain.The DAPIN domain is composed mostly of -helixes and is a protein-protein interaction domain capable of binding other DAPIN domains.The HIN-200 domain has been shown to bind directly to DNA, which, along with the binding of another protein ASC, results in the activation of Caspase-1.
- Shipping Conditions:
- Blue Ice