E-AB-10955
CERK Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-10955
- Additional Names:
- Acylsphingosine kinase,CERK1,Ceramide kinase,Cerk,KIAA1646,LK4,Lipid kinase 4,Lipid kinase LK4,dA59H18.2,dA59H18.3,hCERK
- Application:
- IHC
- Concentration:
- 0.3 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human CERK
- Uniprot:
- Q8TCT0
- Synonyms:
- acylsphingosine kinase;ceramide kinase;dA59H18.2;dA59H18.3;hCERK;lipid kinase 4;lipid kinase LK4;LK4
- Extra Details:
- CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation. Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides.
- Shipping Conditions:
- Blue Ice