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E-AB-10934

OLR1 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-10934
Additional Names:
C-type lectin domain family 8 member A,CLEC8A,Lectin like oxLDL receptor 1,Lectin like oxidized LDL receptor 1,Lectin type oxidized LDL receptor 1,Lectin-like oxLDL receptor 1,Lectin-like oxidized LDL receptor 1,Lectin-type oxidized LDL rece,hLOX 1,hLOX-1
Application:
IHC
Concentration:
0.5 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human OLR1
Uniprot:
P78380
Synonyms:
C-type lectin domain family 8 member A;CLEC8A;hLOX-1;Lectin-like oxidized LDL receptor 1;lectin-type oxidized LDL receptor 1;LOX1;LOXIN;ox LDL receptor 1;oxidized low density lipoprotein (lectin-like) receptor 1;oxidized low-density lipoprotein receptor 1;oxidized low-density lipoprotein receptor 1, soluble form;SCARE1;scavenger receptor class E, member 1;SLOX1
Extra Details:
This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.
Shipping Conditions:
Blue Ice