E-AB-10916
PIM2 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-10916
- Additional Names:
- OTTHUMP00000025825,PIM2,PIM2 Oncogene,Pim 2 oncogene,Pim 2h,Pim-2h,Pim2h,Proto Oncogene PIM2,Proto-oncogene Pim-2 (serine threonine kinase),Serine/threonine kinase PIM2,Serine/threonine-protein kinase Pim-2
- Application:
- IHC
- Concentration:
- 0.3 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human PIM2
- Uniprot:
- Q9P1W9
- Synonyms:
- pim-2 oncogene;pim-2h;proto-oncogene Pim-2 (serine threonine kinase);serine/threonine-protein kinase pim-2
- Extra Details:
- This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival. Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression, the regulation of cap-dependent protein translation and through survival signaling by phosphorylation of a pro-apoptotic protein, BAD. Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase transcriptional activity.
- Shipping Conditions:
- Blue Ice