E-AB-10875
TLR3 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-10875
- Additional Names:
- CD283,CD283 antigen,IIAE2,TLR 3,TLR3,Tlr3,Toll Like Receptor 3,Toll-like receptor 3
- Application:
- IHC
- Concentration:
- 0.5 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human TLR3
- Uniprot:
- O15455
- Synonyms:
- CD283;IIAE2;IMD83;toll-like receptor 3
- Extra Details:
- The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons.
- Shipping Conditions:
- Blue Ice