E-AB-10872
TLR5 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-10872
- Additional Names:
- FLJ10052,MGC126430,MGC126431,SLEB1,TIL 3,TIL3,TLR 5,TLR5,Tlr5,Toll like receptor 5,Toll like receptor 5 precursor,Toll-like receptor 5,Toll/interleukin 1 receptor like protein 3,Toll/interleukin-1 receptor-like protein 3
- Application:
- IHC
- Concentration:
- 0.3 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human TLR5
- Uniprot:
- O60602
- Synonyms:
- MELIOS;SLE1;SLEB1;systemic lupus erythematosus susceptibility 1;TIL3;toll-like receptor 5;toll/interleukin-1 receptor-like protein 3
- Extra Details:
- This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.
- Shipping Conditions:
- Blue Ice