APLF Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:: E-AB-10816
Additional Names:: 2010301N04Rik,AI452191,APLF,Aplf,Aprataxin and PNK-like factor,Apurinic-apyrimidinic endonuclease APLF,C2orf13,PNK and APTX like FHA protein,PNK and APTX-like FHA domain-containing protein,RGD1565557,XIP1,XRCC1 interacting protein 1,XRCC1-interacting prot
Application:: IHC
Concentration:: 0.5 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant protein of human APLF
Uniprot:: Q8IW19
Synonyms:: APFL;aprataxin and PNK-like factor;aprataxin- and PNK-like factor;apurinic-apyrimidinic endonuclease APLF;C2orf13;PALF;PNK and APTX-like FHA domain-containing protein;PNK and APTX-like FHA protein;Xip1;XRCC1-interacting protein 1;ZCCHH1;zinc finger, CX5CX6HX5H motif containing 1
Extra Details:: C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks. Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro.