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E-AB-10808

ANAPC2 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-10808
Additional Names:
ANC2,APC2,Anaphase promoting complex subunit 2,Anaphase-promoting complex subunit 2,Cyclosome subunit 2,KIAA1406,OTTHUMP00000022692,RP11 350O14.5,anapc2
Application:
IHC
Concentration:
0.3 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human ANAPC2
Uniprot:
Q9UJX6
Synonyms:
anaphase-promoting complex subunit 2;APC2;cyclosome subunit 2
Extra Details:
A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, whicHuman, Mouseay also be involved in ubiquitin-mediated degradation.
Shipping Conditions:
Blue Ice