E-AB-10614
CCDC99 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-10614
- Additional Names:
- AA409762,Arsenite related gene 1 protein,Arsenite-related gene 1 protein,CCDC 99,Ccdc99,Coiled coil domain containing 99,Coiled-coil domain-containing protein 99,FLJ20364,FLJ40690,MGC124977,Protein Spindly,Rh,hSpindly,rhabdomyosarcoma antigen MU RMS 40.4A
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human SPDL1
- Uniprot:
- Q96EA4
- Synonyms:
- arsenite-related gene 1 protein;CCDC99;coiled-coil domain-containing protein 99;protein Spindly;rhabdomyosarcoma antigen MU-RMS-40.4A;rrhabdomyosarcoma antigen protein MU-RMS-40.4A;Spindle apparatus coiled-coil domain-containing protein 1
- Extra Details:
- Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. Interacts with KNTC1 and ZW10. These interactions appear weak and may be transient or indirect.
- Shipping Conditions:
- Blue Ice