E-AB-10554
PRMT7 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-10554
- Additional Names:
- ANM7,FLJ10640,Histone-arginine N-methyltransferase PRMT7,KIAA1933,Myelin basic protein arginine N methyltransferase,OTTHUMP00000174863,PRMT7,Protein arginine N-,Protein arginine methyltransferase 7,[Myelin basic protein]-arginine N-methyltransferase PRMT7
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human PRMT7
- Uniprot:
- Q9NVM4
- Synonyms:
- [Myelin basic protein]-arginine N-methyltransferase PRMT7;histone-arginine N-methyltransferase PRMT7;protein arginine N-methyltransferase 7;SBIDDS
- Extra Details:
- Protein arginine methyltransferase 7 is a protein that in humans is encoded by the PRMT7 gene.Arginine methylation is an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, using S-adenosylmethionine (AdoMet) as the methyl donor.Arginine methylation is implicated in signal transduction, RNA transport, and RNA splicing.May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers.Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT).
- Shipping Conditions:
- Blue Ice