E-AB-10535
SPDEF Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-10535
- Additional Names:
- PDEF,PROSTATE EPITHELIUM SPECIFIC ETS TRANSCRIPTION FACTOR,PSE,Prostate derived Ets factor,Prostate epithelium-specific Ets transcription factor,Prostate specific Ets,Prostate-derived Ets factor,Prostate-specific Ets,RP11-375E1__A.3,SAM POINTED ,bA375E1.3
- Application:
- IHC
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human SPDEF
- Uniprot:
- O95238
- Synonyms:
- bA375E1.3;PDEF;prostate epithelium-specific Ets transcription factor;prostate-derived Ets factor;prostate-specific Ets;SAM pointed domain-containing Ets transcription factor
- Extra Details:
- The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice