E-AB-10477
MUTYH Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-10477
- Additional Names:
- A/G specific adenine DNA glycosylase,A/G-specific adenine DNA glycosylase,Adenine DNA glycosylase,CYP2C,E. coli,MGC4416,MUTYH,MYH,MutY,MutY (E. coli) homolog,MutY homolog,MutY homolog (E. coli),Mutyh,hMYH,homolog of,rMYH
- Application:
- IHC, WB
- Concentration:
- 0.3 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human MUTYH
- Uniprot:
- Q9UIF7
- Synonyms:
- A/G-specific adenine DNA glycosylase;adenine DNA glycosylase;mutY homolog;mutY-like protein;MYH
- Extra Details:
- This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice