E-AB-10471
MLH1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-10471
- Additional Names:
- COCA 2,COCA2,DNA mismatch repair protein Mlh1,FCC 2,FCC2,HNPCC,HNPCC 2,HNPCC2,MGC5172,MLH 1,MLH1,MutL homolog 1,MutL homolog 1 (E. coli),MutL homolog 1 colon cancer nonpolyposis type 2,colon cancer,hMLH 1,hMLH1,nonpolyposis type 2 (E.
- Application:
- IHC
- Concentration:
- 0.8 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human MLH1
- Uniprot:
- P40692
- Synonyms:
- COCA2;DNA mismatch repair protein Mlh1;FCC2;hMLH1;HNPCC;HNPCC2;MMRCS1;mutL homolog 1, colon cancer, nonpolyposis type 2;MutL protein homolog 1
- Extra Details:
- This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
- Shipping Conditions:
- Blue Ice