E-AB-10451
MCM6 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-10451
- Additional Names:
- DNA replication licensing factor MCM6,MCG40308,MCM6,MCM6 minichromosome maintenance deficient 6,MCM6 minichromosome maintenance deficient 6 (MIS5 homolog,Mcm6,Minichromosome maintenance complex component 6,Minichromosome maintenance deficient (m,S. pombe)
- Application:
- IHC, WB
- Concentration:
- 0.6 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human MCM6
- Uniprot:
- Q14566
- Synonyms:
- DNA replication licensing factor MCM6;MCG40308;MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe);minichromosome maintenance deficient (mis5, S. pombe) 6;Mis5;P105MCM
- Extra Details:
- The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication.The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins.The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme.The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.
- Shipping Conditions:
- Blue Ice