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E-AB-10409

IRAK4 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-10409
Additional Names:
IL-1 receptor-associated kinase 4,IPD1,IRAK 4,IRAK-4,IRAK4,IRAK4 mutated form 1,Interleukin 1 receptor associated kinase 4 mutant form 1,Interleukin-1 receptor-associated kinase 4,Interleukin1 receptor associated kinase 4,LOC 51135,NY REN ,NY REN 64
Application:
IHC
Concentration:
0.6 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human IRAK4
Uniprot:
Q9NWZ3
Synonyms:
IMD67;interleukin-1 receptor-associated kinase 4;IPD1;IRAK-4;NY-REN-64;REN64;renal carcinoma antigen NY-REN-64
Extra Details:
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Shipping Conditions:
Blue Ice