E-AB-10290
DOK1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-10290
- Additional Names:
- DOK 1,DOK1,Docking protein 1,Docking protein 1 62kD,Downstream of tyrosine kinase 1,P62DOK,p62(dok),pp62
- Application:
- WB
- Concentration:
- 0.5 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human DOK1
- Uniprot:
- Q99704
- Synonyms:
- docking protein 1;Downstream of tyrosine kinase 1;p62(dok);P62DOK;pp62
- Extra Details:
- The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
- Shipping Conditions:
- Blue Ice