E-AB-10288
DNMT3A Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-10288
- Additional Names:
- DNA (cytosine 5) methyltransferase 3 alpha,DNA (cytosine 5) methyltransferase 3A,DNA (cytosine-5)-methyltransferase 3A,DNA MTase HsaIII,DNA cytosine methyltransferase 3A2,DNA methyltransferase 3 alpha,DNA methyltransferase 3a,DNA methyltransferase HsaIIIA
- Application:
- IHC
- Concentration:
- 0.6 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human DNMT3A
- Uniprot:
- Q9Y6K1
- Synonyms:
- cysteine methyltransferase DNMT3A;DNA (cytosine-5-)-methyltransferase 3 alpha;DNA (cytosine-5)-methyltransferase 3A;DNA cytosine methyltransferase 3A2;DNA methyltransferase HsaIIIA;DNA MTase HsaIIIA;DNMT3A2;HESJAS;M.HsaIIIA;TBRS
- Extra Details:
- CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Shipping Conditions:
- Blue Ice