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E-AB-10260

CRTAM Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-10260
Additional Names:
CD355,CRTAM,Class I MHC restricted T cell associated molecule,Class-I MHC-restricted T-cell-associated molecule,Cytotoxic and regulatory T cell molecule,Cytotoxic and regulatory T-cell molecule
Application:
IHC, WB
Concentration:
0.3 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human CRTAM
Uniprot:
O95727
Synonyms:
CD355;class-I MHC-restricted T-cell-associated molecule;cytotoxic and regulatory T-cell molecule
Extra Details:
The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A, MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.
Shipping Conditions:
Blue Ice