E-AB-10253
EMC8 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-10253
- Additional Names:
- C16orf2,C16orf4,COX4,COX4 neighbor,COX4AL,CX4NB,Cox4nb,ER membrane protein complex subunit 8,FAM158B,NOC4,Neighbor of COX4,Protein FAM158B,family with sequence similarity 158,member B,neighbor of
- Application:
- IHC, WB
- Concentration:
- 0.4 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human EMC8
- Uniprot:
- O43402
- Synonyms:
- C16orf2;C16orf4;COX4 neighbor;COX4NB;ER membrane protein complex subunit 8;FAM158B;family with sequence similarity 158, member B;neighbor of COX4;NOC4;Protein FAM158B
- Extra Details:
- COX4NB (Neighbor of COX4) is a 210 amino acid protein encoded by the human gene COX4NB. COX4NB belongs to the UPF0172 (NOC4) family and is found on chromosome 16, adjacent to the gene that encodes COX4. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16 through the CREBBP gene which encodes a critical CREB binding protein. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other auto-immune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.
- Shipping Conditions:
- Blue Ice