E-AB-10207
CTNNA1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-10207
- Additional Names:
- 102kDa,Alpha E-catenin,CAP 102,CAP102,Cadherin associated protein,Cadherin associated protein 102kDa,Cadherin-associated protein,Catenin (cadherin associated protein),Catenin (cadherin associated protein) alpha 1 102kDa,Catenin alp,Catenin alpha 1,alpha 1
- Application:
- IHC, WB
- Concentration:
- 0.2 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human CTNNA1
- Uniprot:
- P35221
- Synonyms:
- Alpha E-catenin;alpha-E-catenin;Cadherin-associated protein;CAP102;catenin (cadherin-associated protein), alpha 1, 102kDa;catenin alpha-1;epididymis secretory sperm binding protein;MDPT2;renal carcinoma antigen NY-REN-13
- Extra Details:
- Catenin alpha-1 is a protein that in humans is encoded by the CTNNA1 gene.Associates with the cytoplasmic domain of a variety of cadherins.The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.Can associate with both E- and N-cadherins.Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions.In contrast, cortical actin was found to be mucHuman, Mouseore dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components.
- Shipping Conditions:
- Blue Ice